All blood cells originate in the bone marrow and are derived from a common precursor, the pluripotential stem cell. There are very view of these cells but by mitosis and a feedback control mechanism they supply the demand for blood cells while maintaining their original numbers.After producing two daughter cells by mitotoc division one of daughter cells retains the properties of the pluripotencial cell while the order is committed to produce mature blood cells. The committed stem cell then receives a specific stimulus to differentiate into a blast cell in one of the cell lines. This phase is known as cell differentiation.
The development of blood cell from the blast cell stage progresses through three further phases:
[1] Proliferation: blast cells divide by mitosis to produce large numbers of more mature daughter cells.
[2] Maturation: cells develop toward the functional unit.
[3] Release: mature (functional) cells are allowed into the circulation.
Main Reference:
0 comments:
Post a Comment